{"id":9027,"date":"2024-06-24T19:26:57","date_gmt":"2024-06-24T19:26:57","guid":{"rendered":"https:\/\/www.breakthrought1d.org\/mountainwest\/?p=9027"},"modified":"2025-11-21T16:40:43","modified_gmt":"2025-11-21T16:40:43","slug":"clinical-trial-spotlight","status":"publish","type":"post","link":"https:\/\/www.breakthrought1d.org\/rockymountain\/2024\/06\/24\/clinical-trial-spotlight\/","title":{"rendered":"Clinical Trial Spotlight"},"content":{"rendered":"

Come back to this blog post periodically to read about the clinical trials currently recruiting people just like you!<\/p>\n

DIAGNODE-3<\/h4>\n

Purpose:<\/strong> to explore whether an investigational drug, Diamyd (rhGAD65), is able to preserve the body’s own insulin-producing ability<\/p>\n

What’s required: <\/strong>three injections, followed by a 22-month follow-up period; must be able to travel to Barbara Davis Center<\/p>\n

Who can participate: <\/strong>individuals ages 12 through 29 diagnosed with T1D in the past 6 months who have a certain genetic risk for T1D (HLA haplotype DR3-DQ2)<\/p>\n

Learn more about this study here<\/a>!<\/p>\n

FABULINUS<\/h4>\n

Purpose:\u00a0<\/strong>to test if an investigational study drug, frexalimab, can preserve pancreatic beta cell function in people recently diagnosed with T1D<\/p>\n

What’s required:\u00a0<\/strong>participation for approximately 2.5 years, with study site visits for various testing<\/p>\n

Who can participate:\u00a0<\/strong>individuals ages 12 through 21 newly diagnosed with T1D and on insulin therapy for 90 days or less<\/p>\n

Learn more about this study here<\/a> or by contacting Clive Harston<\/a>!<\/p>\n

FINE-ONE<\/h4>\n

Purpose: <\/strong>to learn if finerenone is safe and effective in preventing the progression of chronic kidney disease in people with T1D<\/p>\n

What’s required:<\/strong> participation for potentially up to 7.5 months, taking study treatments for 6 months, with visits to the study site at least 6 times<\/p>\n

Who can participate: <\/strong>adults over the age of 18 who have lived with T1D for at least one year<\/p>\n

Learn more about this study and your eligibility here<\/a>!<\/p>\n

GLP-1 Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab (GLP-TEP)<\/h4>\n

Purpose:\u00a0<\/strong>to examine if the addition of a GLP-1 receptor agonist can help manage blood sugar levels and improve cardiovascular health in both adults and children<\/p>\n

What’s required:\u00a0<\/strong>meal testing, post-treatment tests, and regular blood draws<\/p>\n

Who can participate:\u00a0<\/strong>children and adults ages 12 through 50 who are in stage 2 T1D and meet specific criteria for body mass index and blood glucose levels<\/p>\n

Learn more about this study and your eligibility here<\/a>!<\/p>\n

JAKPOT T1D<\/h4>\n

Purpose:<\/strong> to see if two different treatments – abrocitinib and ritlecitinib (a new class of autoimmune treatments called Janus kinase [JAK] inhibitors) – can preserve insulin production in people newly diagnosed with T1D<\/p>\n

What’s required: <\/strong>a treatment over 1 year (where you will visit a study site every 3 months for tests), plus a 1-year follow-up phase (where you will visit a study site every 6 months)<\/p>\n

Who can participate:<\/strong> individuals ages 12 through 35 who have been diagnosed with T1D in the past 3 months<\/p>\n

Learn more about this study and share your interest in participating here<\/a>!<\/p>\n

Patients’ and Carers’ Perceptions on Routine Mental Health Screening in Pediatric Diabetes Care<\/h4>\n

Purpose:\u00a0<\/strong>to understand how people with diabetes and their caregivers perceive their healthcare team’s role in screening for psychological concerns<\/p>\n

What’s required:<\/strong> a 15-minute survey<\/p>\n

Who can participate:\u00a0<\/strong>individuals ages 12 through 18 who live with diabetes, or caregivers of someone who matches that criteria<\/p>\n

Take the survey here<\/a>!<\/p>\n

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease (SUGARNSALT) Trial<\/h4>\n

Purpose:<\/strong> to examine the potential of an SGLT inhibitor, sotagliflozin, to prevent or delay the progression to kidney failure in T1D<\/p>\n

What’s required:\u00a0<\/strong>ability to participate in a 3-year trial<\/p>\n

Who can participate:<\/strong> individuals ages 19 through 75 who have been living with T1D for at least 8 years and have chronic kidney disease<\/p>\n

Learn more about this study here<\/a>!<\/p>\n

A Study of Tirzepatide Compared With Placebo in Adults with T1D and Obesity or Overweight (SURPASS-T1D-1)<\/h4>\n

Purpose:\u00a0<\/strong>to determine whether tirzepatide (Mounjaro or Zepbound) can improve blood glucose in people with T1D who are obese or overweight<\/p>\n

What’s required:\u00a0<\/strong>participation in on-site testing for approximately 49 weeks<\/p>\n

Who can participate:\u00a0<\/strong>adults 18 and older who have been on external insulin for at least one year who also have an HbA1c of 7-10.5%, a body mass index of 25 or higher, and a stable weight for at least 90 days prior to screening<\/p>\n

Learn more about this study and your eligibility here<\/a>!<\/p>\n

The Teen Interview on Diabetes Eating Survey (TIDES)<\/h4>\n

Purpose:<\/strong> to better understand how teenagers with T1D answer standard survey questions about diabetes and eating in order to see if updates need to be made<\/p>\n

What’s required:<\/strong> the teen would complete brief questionnaires, followed by a virtual interview with a study staff member<\/p>\n

Who can participate: <\/strong>teens with T1D ages 13 through 17<\/p>\n

Incentive: <\/strong>compensation for time<\/p>\n

Find out if you’re eligible here<\/a>!<\/p>\n

Type 1 Diabetes Adolescents for healthier Lifestyle (T1DAL) Study<\/h4>\n

Purpose: <\/strong>to test out a new healthy lifestyles program designed specifically for teenagers with T1D<\/p>\n

What’s required:\u00a0<\/strong>the teen would attend one 75-minute virtual session per week for 16 weeks, with each group containing 4-8 other teens<\/p>\n

Who can participate:<\/strong> teens ages 13 through 18 who have been diagnosed with T1D for at least 6 months<\/p>\n

Incentive:<\/strong> teens can earn up to $125 and parents\/caregivers can earn up to $80<\/p>\n

Fill out this survey<\/a> to share your interest!<\/p>\n

For a treatment, drug, or device to make it into the hands of people with T1D, it first needs your<\/strong> help to complete a vital step – a clinical trial. Learn more about how you can impact T1D breakthroughs through research and clinical trials here<\/a>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Come back to this blog post periodically to read about the clinical trials currently recruiting people just like you! DIAGNODE-3 Purpose: to explore whether an investigational drug, Diamyd (rhGAD65), is able to preserve the body’s own insulin-producing ability What’s required:…<\/p>\n","protected":false},"author":1317,"featured_media":9043,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"ep_exclude_from_search":false,"publish_on_app_meta":"True","iawp_total_views":5,"footnotes":"","bt1d_storytelling_post":false,"bt1d_storytelling_more_posts":[]},"topics":[122,31,16],"class_list":["post-9027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","jdrf_topic-awareness","jdrf_topic-clinical-trials","jdrf_topic-research"],"acf":[],"yoast_head":"\nClinical Trial Spotlight - Rocky Mountain Chapter<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.breakthrought1d.org\/rockymountain\/2024\/06\/24\/clinical-trial-spotlight\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical Trial Spotlight - Rocky Mountain Chapter\" \/>\n<meta property=\"og:description\" content=\"Come back to this blog post periodically to read about the clinical trials currently recruiting people just like you! 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