Showing 1-10 of 17 grants

Title Institution Researcher Program Duration Total Award Amount
Safe and Immune Cloaked Stem Cell-Derived Beta-Cells: Treatment for Type 1 Diabetes Mellitus Sinai Health System Andras Nagy Cures 01-October-2022 to 30-September-2026 $1,474,390.51
Targeting Novel GPCRs to Promote Beta Cell Survival Sunnybrook Research Institute Robert Screaton Cures 01-February-2022 to 28-February-2026 $110,000.00
Regenerating Human Pancreatic β Cells to Treat Diabetes Sunnybrook Research Institute Robert Screaton Cures 01-May-2022 to 31-May-2026 $900,000.00
mRNA/LNP-based Epigenetic Immunomodulation to Restore Tolerance in T1D The Governing Council of the University of Toronto BOWEN LI Cures 01-April-2026 to 31-March-2027 $199,998.79
Picosecond Infrared Laser (PIRL)-based spatial imaging mass spectrometry (proteomics) and transcriptomics of beta-cells in live human pancreas slices afflicted by T1D T-cell immune injury The Governing Council of the University of Toronto Herbert Gaisano Cures 01-April-2026 to 31-March-2027 $199,430.00
Vascular regenerative biomaterial (MAA) for islet transplantation The Governing Council of the University of Toronto Michael Sefton Cures 01-August-2021 to 30-November-2025 $506,807.41
Synthetic vascularizing biomaterial platform for subcutaneous islet transplantation and immunomodulation The Governing Council of the University of Toronto Sean Kinney Cures 01-March-2025 to 29-February-2028 $237,690.00
Development of targeted nanoparticles for delivering therapeutics to islet cells for treatment of T1D The Governing Council of the University of Toronto Xiao Yu (Shirley) Wu Cures 01-April-2023 to 31-March-2026 $899,710.00
Manufacturing high quality cGMP-compatible SC-islets University Health Network Maria Cristina Nostro Cures 01-May-2025 to 30-April-2026 $1,498,919.50
Macrophage-Mediated Strategies for Promoting Vascularization and Immunotolerance in Islet Cell Replacement Therapies University Health Network Maria Cristina Nostro Cures 01-September-2024 to 31-August-2026 $499,987.19