Showing 1-10 of 15 grants

Title Institution Researcher Program Duration Total Award Amount
Dissecting HLA Mechanisms in T1D, SLE, and MS Through High-Throughput Self-Antigen Profiling The University of Chicago Aly Khan Cures 01-September-2025 to 31-August-2026 $150,000.00
Investigating the role of integrated stress response in type 1 diabetes The University of Chicago Charanya Muralidharan Cures 01-March-2023 to 28-February-2026 $209,066.00
Development of β-Cell Targeted Lipid Nanoparticle Therapeutics The University of Chicago Jacob Ryan Enriquez Cures 01-March-2025 to 29-February-2028 $247,790.00
A pilot study assessing the safety of using a monoclonal antibody against CD40 ligand to achieve a calcineurin inhibitor-free immunosuppression regimen in patients with type 1 diabetes mellitus (T1D) and problematic hypoglycemia undergoing islet cell transplantation The University of Chicago Piotr Witkowski Cures 01-February-2025 to 31-January-2027 $1,000,000.00
A pilot study assessing the safety of using a monoclonal antibody against CD40 ligand to achieve a calcineurin inhibitor-free immunosuppression regimen in patients with type 1 diabetes mellitus (T1D) and problematic hypoglycemia undergoing islet cell transplantation The University of Chicago Piotr Witkowski Cures 01-February-2024 to 31-January-2026 $250,000.00
Safety and efficacy assessment of Tegoprubart and calcineurin inhibitors- free immunosuppression therapy for pancreatic islet transplantation in patients with t1DM and chronic kidney disease. The University of Chicago Piotr Witkowski Cures 01-September-2025 to 31-August-2029 $8,500,000.00
Engineered Nanoparticles for Beta Cell-Targeted Therapeutics The University of Chicago Raghavendra Mirmira Cures 01-April-2023 to 31-March-2026 $897,822.00
A New Preparation of the Intact Eye for Measurements of Retinal Dysfunction in Acute Hyperglycemia and Early Diabetes Northwestern University Gregory Schwartz Improving Lives 01-October-2023 to 30-September-2025 $406,927.40
Assessment of a Tolerogenic Nanoparticle in a Humanized Mouse Islet Transplantation Model Northwestern University Jacqueline Burke Cures 01-April-2024 to 31-March-2026 $499,746.76
Validation of a Tolerogenic Nanotherapy for Islet Transplantation in a Non-Human Primate Model Northwestern University Jacqueline Burke Cures 01-July-2023 to 30-June-2026 $998,275.64