Showing 11-18 of 18 grants

Title Institution Researcher Program Duration Total Award Amount
Expanding the Therapeutic and Targeting Capacity of Lipid Nanoparticles for Beta-Cell Protection The University of Chicago Raghavendra Mirmira Cures 01-September-2026 to 31-August-2028 $471,201.00
A pilot study assessing the safety of using a monoclonal antibody against CD40 ligand to achieve a calcineurin inhibitor-free immunosuppression regimen in patients with type 1 diabetes mellitus (T1D) and problematic hypoglycemia undergoing islet cell transplantation The University of Chicago Piotr Witkowski Cures 01-February-2025 to 31-January-2027 $1,500,000.00
A pilot study assessing the safety of using a monoclonal antibody against CD40 ligand to achieve a calcineurin inhibitor-free immunosuppression regimen in patients with type 1 diabetes mellitus (T1D) and problematic hypoglycemia undergoing islet cell transplantation The University of Chicago Piotr Witkowski Cures 01-February-2024 to 31-October-2026 $250,000.00
Safety and efficacy assessment of Tegoprubart and calcineurin inhibitors- free immunosuppression therapy for pancreatic islet transplantation in patients with t1DM and chronic kidney disease. The University of Chicago Piotr Witkowski Cures 01-September-2025 to 31-August-2029 $8,500,000.00
MDA5 and TRIM21 in β-cell inflammatory signaling and autoimmunity The University of Chicago Kerim Kaylan Cures 01-July-2026 to 30-June-2028 $100,000.00
Development of β-Cell Targeted Lipid Nanoparticle Therapeutics The University of Chicago Jacob Ryan Enriquez Cures 01-March-2025 to 29-February-2028 $247,790.00
Interferons and the Integrated Stress Response: Converging Pathways in β Cell Dysfunction in Type 1 Diabetes The University of Chicago Charanya Muralidharan Cures 01-March-2026 to 28-February-2029 $285,000.00
Dissecting HLA Mechanisms in T1D, SLE, and MS Through High-Throughput Self-Antigen Profiling The University of Chicago Aly Khan Cures 01-September-2025 to 31-August-2026 $150,000.00