Showing 1-10 of 14 grants

Title Institution Researcher Program Duration Total Award Amount
ROLE OF ZBED3 IN BETA CELL STRESS RESPONSE AND VULNERABILITY AGAINST AUTOIMMUNITY Indiana Biosciences Research Institute Erica Cai Cures 01-March-2023 to 29-February-2028 $999,737.71
Targeting ER cargo proteins for beta cell protection against cellular stress and autoimmunity Indiana Biosciences Research Institute Erica Cai Cures 01-September-2023 to 31-August-2026 $499,934.12
Genome-scale CRISPR screens identify ER export cargo proteins as mediators for β-cell stress response and antigen presentation Indiana Biosciences Research Institute Isabela Lovizutto Iessi Longo Cures 01-March-2023 to 28-February-2026 $135,307.11
Exploiting SDF2L1 to protect against beta cell death and dysfunction in T1D Indiana Biosciences Research Institute Michael Kalwat Cures 01-December-2024 to 30-November-2027 $748,169.00
Preclinical evaluation of SERCA2 activators for pancreatic beta-cell protection in T1D Neurodon LLC Russell Dahl Cures 01-June-2022 to 31-October-2025 $920,000.00
Evaluation of Oxidized Insulin as a Biomarker and Therapeutic Target in Type 1 Diabetes Trustees of Indiana University Amelia Linnemann Cures 01-October-2023 to 30-September-2025 $560,000.00
Defining the role of islet-derived extracellular vesicle PD-L1 cargo in type-1 diabetes Trustees of Indiana University Chaitra Rao Cures 01-March-2024 to 30-April-2027 $228,537.45
Targeting type 1 Diabetes through Polyamines with DFMO Trustees of Indiana University Emily Sims Cures 01-October-2022 to 30-September-2026 $3,693,701.00
Investigating Combinatorial Use of Inhibitors of Focal Adhesion Kinase and PFKFB3 for Reversal of Type 1 Diabetes Trustees of Indiana University Jon Piganelli Cures 01-August-2023 to 30-June-2025 $334,595.29
SOLUBLE LYMPHOCYTE ACTIVATION GENE-3 (s-LAG-3): A POTENTIAL SURROGATE MARKER FOR TYPE-1 DIABETES PROGRESSION AND IMMUNOTHERAPY SUCCESS Trustees of Indiana University Jon Piganelli Cures 01-July-2025 to 30-June-2026 $153,000.00