Showing 131-140 of 333 grants

Title Institution Researcher Program Duration Total Award Amount
Network-based Systems Biology for T1D Drug Repositioning The Regents of the University of California, Los Angeles Xia Yang Improving Lives 01-May-2021 to 30-November-2025 $780,961.09
Investigation of novel local immunomodulating strategies to enhance islet transplantation for T1D The Methodist Hospital Research Institute Alessandro Grattoni Cures 01-July-2022 to 30-June-2026 $962,995.99
Prevascularized encapsulation platform with local immunosuppression for Islet transplantation The Methodist Hospital Research Institute Alessandro Grattoni Cures 01-August-2021 to 31-January-2026 $660,000.00
Tolerance inducing NanoLymph for in vivo generation of islet autoantigen-specific regulatory T cells The Methodist Hospital Research Institute Ying Xuan Chua Cures 01-April-2025 to 31-March-2026 $200,000.00
Defining the cell surface glycoproteome and glycome of human islets to enable single cell analysis of human β-cells The Medical College of Wisconsin Inc. John Corbett Cures 01-October-2022 to 30-September-2025 $750,000.00
Transcriptional modulation by BET bromodomain inhibitors in beta cells The Medical College of Wisconsin Inc. Joshua Nord Cures 01-March-2023 to 28-February-2026 $221,638.00
A prodrug system for targeted activation of small molecules in beta cells The Brigham and Women’s Hospital, Inc. Amit Choudhary Cures 01-February-2024 to 31-January-2027 $2,250,000.00
Expanding Access to T1D Care through the PEN-Plus Strategy The Brigham and Women’s Hospital, Inc. Gene Bukhman Mission 01-August-2024 to 31-July-2027 $5,999,961.29
Exploiting CRISPR Strategy to Modify T-Cell Lipid Signaling and Mitigate T1D Development The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham Sasanka Ramanadham Cures 01-May-2023 to 30-April-2025 $199,989.05
Novel Combination Regimen Therapy to Modulate Pro- and Anti-inflammatory Lipid Signaling to Counter T1D The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham Sasanka Ramanadham Cures 01-July-2022 to 30-June-2025 $600,000.00