Showing 191-200 of 328 grants

Title Institution Researcher Program Duration Total Award Amount
A prodrug system for targeted activation of small molecules in beta cells The Brigham and Women’s Hospital, Inc. Amit Choudhary Cures 01-February-2024 to 31-January-2027 $2,250,000.00
Expanding Access to T1D Care through the PEN-Plus Strategy The Brigham and Women’s Hospital, Inc. Gene Bukhman Mission 01-August-2024 to 31-July-2027 $5,999,961.29
Defining the cell surface glycoproteome and glycome of human islets to enable single cell analysis of human β-cells The Medical College of Wisconsin Inc. John Corbett Cures 01-October-2022 to 30-September-2025 $750,000.00
Transcriptional modulation by BET bromodomain inhibitors in beta cells The Medical College of Wisconsin Inc. Joshua Nord Cures 01-March-2023 to 28-February-2026 $221,638.00
Investigation of novel local immunomodulating strategies to enhance islet transplantation for T1D The Methodist Hospital Research Institute Alessandro Grattoni Cures 01-July-2022 to 30-June-2026 $962,995.99
Prevascularized encapsulation platform with local immunosuppression for Islet transplantation The Methodist Hospital Research Institute Alessandro Grattoni Cures 01-August-2021 to 31-January-2026 $660,000.00
Tolerance inducing NanoLymph for in vivo generation of islet autoantigen-specific regulatory T cells The Methodist Hospital Research Institute Ying Xuan Chua Cures 01-April-2025 to 31-March-2026 $200,000.00
Antigen-specific immunotherapies based on ignored ß-cell antigen determinants. The Regents of the University of California, Los Angeles Daniel Kaufman Cures 01-October-2024 to 30-September-2026 $573,101.00
Multiplex in vivo imaging of the dynamics of immune-mediated rejection of allogenic islet grafts The Regents of the University of California, Los Angeles Oluwatayo Ikotun Cures 01-February-2024 to 31-January-2027 $749,996.25
Network-based Systems Biology for T1D Drug Repositioning The Regents of the University of California, Los Angeles Xia Yang Improving Lives 01-May-2021 to 30-November-2025 $780,961.09