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Showing 231-240 of 345 grants

Title Institution Researcher Program Duration Total Award Amount
A pilot study assessing the safety of using a monoclonal antibody against CD40 ligand to achieve a calcineurin inhibitor-free immunosuppression regimen in patients with type 1 diabetes mellitus (T1D) and problematic hypoglycemia undergoing islet cell transplantation The University of Chicago Piotr Witkowski Cures 01-February-2025 to 31-January-2027 $1,500,000.00
Safety and efficacy assessment of Tegoprubart and calcineurin inhibitors- free immunosuppression therapy for pancreatic islet transplantation in patients with t1DM and chronic kidney disease. The University of Chicago Piotr Witkowski Cures 01-September-2025 to 31-August-2029 $8,500,000.00
Engineered Nanoparticles for Beta Cell-Targeted Therapeutics The University of Chicago Raghavendra Mirmira Cures 01-April-2023 to 31-August-2026 $897,822.00
Role of β-cell Golgi dysfunction in Type 1 diabetes pathogenesis The University of Iowa Samuel Stephens Cures 01-June-2024 to 31-May-2027 $750,000.00
The Development of 3-β-hydroxybutyrate binding protein based electrochemical micro-sensor and its application for CKM system The University of North Carolina at Chapel Hill Koji Sode Improving Lives 01-October-2022 to 30-September-2026 $799,999.96
Engineering B Cell–Targeted Microparticles to Induce Regulatory Immunity in Type 1 Diabetes The University of North Carolina at Chapel Hill Kristy Ainslie Cures 01-April-2026 to 31-March-2027 $200,000.00
GABP regulation of human beta cell proliferation The University of Texas Health Science Center at Houston Richard Cox Cures 01-September-2024 to 31-August-2026 $200,000.00
Development of Low Cost, High Precision Nano Pumps for Insulin Delivery Torramics Inc. Sergey Gimelshein Improving Lives 01-March-2023 to 31-August-2026 $1,493,212.43
Achieving persistent presentation of self-antigens to reestablish tolerance and prevent autoimmune diabetes Trustees of Columbia University in the City of New York Camillo Bechi Genzano Cures 01-March-2025 to 29-February-2028 $256,285.00
Improving pig islet transplant efficacy in a preclinical baboon diabetes model with induced immune tolerance to the xenografts Trustees of Columbia University in the City of New York Megan Sykes Cures 01-June-2024 to 31-May-2026 $599,999.94