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Showing 231-240 of 328 grants

Title Institution Researcher Program Duration Total Award Amount
Improving pig islet transplant efficacy in a preclinical baboon diabetes model with induced immune tolerance to the xenografts Trustees of Columbia University in the City of New York Megan Sykes Cures 01-June-2024 to 31-May-2026 $599,999.94
In vivo analysis of human islet graft infiltration and its immunomodulation by antigen-specific therapy Trustees of Columbia University in the City of New York Remi Creusot Cures 01-August-2022 to 31-July-2025 $699,997.82
Low level engraftment of modified HSCs for continuous and omnipresent autoantigen exposure as requirements to establish tolerance Trustees of Columbia University in the City of New York Remi Creusot Cures 01-June-2024 to 31-January-2026 $188,704.16
Evaluation of Oxidized Insulin as a Biomarker and Therapeutic Target in Type 1 Diabetes Trustees of Indiana University Amelia Linnemann Cures 01-October-2023 to 30-September-2025 $560,000.00
Defining the role of islet-derived extracellular vesicle PD-L1 cargo in type-1 diabetes Trustees of Indiana University Chaitra Rao Cures 01-March-2024 to 30-April-2027 $228,537.45
Targeting type 1 Diabetes through Polyamines with DFMO Trustees of Indiana University Emily Sims Cures 01-October-2022 to 30-September-2026 $3,693,701.00
Investigating Combinatorial Use of Inhibitors of Focal Adhesion Kinase and PFKFB3 for Reversal of Type 1 Diabetes Trustees of Indiana University Jon Piganelli Cures 01-August-2023 to 30-June-2025 $334,595.29
SOLUBLE LYMPHOCYTE ACTIVATION GENE-3 (s-LAG-3): A POTENTIAL SURROGATE MARKER FOR TYPE-1 DIABETES PROGRESSION AND IMMUNOTHERAPY SUCCESS Trustees of Indiana University Jon Piganelli Cures 01-July-2025 to 30-June-2026 $153,000.00
CGM-Derived Glucose Dynamic Index as Diagnostic Marker for Progression to Type 1 Diabetes Trustees of Indiana University Viral Shah Cures 01-November-2024 to 31-October-2027 $900,000.00
Relationship of Time-In-Range with microvascular complications in type 1 diabetes Trustees of Indiana University Viral Shah Improving Lives 01-February-2024 to 31-July-2025 $71,123.95