Participate in a Clinical Trial

Minnesota and Dakotas Chapter

Participating in a clinical trial is a great way to further research in curing, preventing, and treating type 1 diabetes (T1D) and its complications. Learn more below about the clinical trials currently recruiting in your area.

Greater Twin Cities Metro

U of M – Clinical Trials

(1 of 4) For the Newly Diagnosed:

The JAKPOT Study is recruiting participants ages 12-35 within 100 days of their T1D diagnosis with an A1C <10%. TrialNet researchers are testing two different treatments- abrocitinib and ritlecitinib-to see if either or both can preserve insulin production in people newly diagnosed with type 1 diabetes. Researchers believe these JAK inhibitors may be able to calm the immune system’s attack on cells that make insulin, while also reducing stress to these cells.

 

(2 of 4) For those with a family history of T1D:

TrialNet screening is offered at no cost to eligible individuals to evaluate their personal risk of developing T1D. This unique screening can identify the early stages of T1D years before any symptoms appear.  It also helps researchers learn more about how T1D develops and plan new studies exploring ways to prevent it. Eligible participants are between the ages of 2.5 and 45 years and have a parent, brother/sister, or child with T1D, between the ages of 2.5 and 20 years and have an aunt/uncle, cousin, grandparent, niece/nephew, or half-brother/sister with T1D, and have NOT been diagnosed with T1D.

 

(3 of 4) For adults with T1D:

FAM (Follower, Action Plan, and Remote Monitoring) Intervention to Reduce Severe Hyperglycemia in Adults with Type 1 Diabetes Mellitus at Risk for Diabetic Ketoacidosis (DKA).

 

(4 of 4) For adults with T1D:

DREAM Study – Diabetes related to Acute Pancreatitis and its mechanisms.

 

HealthPartners International Diabetes Center – Clinical Trials

(1 of 3) For children with T1D currently using OmniPod 5:

Safety and Efficacy of the Omnipod® SmartAdjust 2.0 System Compared to the Omnipod® 5 System in Individuals with Type 1 Diabetes (STRIVE). Purpose of study: To trial the investigational Omnipod 5 Smart Adjust 2.0 (SA2.0), featuring a lower target (100 mg/dL) and an updated adaptive insulin algorithm. Over 3-4 months, participants will attend 4-5 office visits and have the opportunity to use the new system. This version is not yet FDA approved and adjusts insulin delivery based on user-set glycemic targets and Total Daily Insulin (TDI).

 

(2 of 3) For adults with T1D:

Luna Automated Insulin Delivery for Multiple Daily Injectors (AID4MDI). Purpose of study: This study will be testing a new investigational insulin delivery system designed to be worn just at night by individuals with type 1 diabetes who take their insulin by injections. This is being done to see if the study system lowers blood sugars for those who may have high blood sugar during sleep and when they wake up. The Luna System works with a person’s continuous glucose monitor (CGM) to provide small amounts of rapid-acting insulin during sleep and does not replace other insulins you are taking. It is investigational, meaning it hasn’t yet been cleared by the FDA to be sold on the market. The study lasts about 17 weeks and involves putting the device on before bed for about 13 of those weeks.

 

(3 of 3) For children & adults with T1D:

Frequency of Ketosis in People Living with Diabetes or Other Medical Conditions. Purpose of study: To use the investigational FreeStyle Libre X Continuous Glucose Monitoring System to collect both ketone and glucose levels, and to learn about how often elevated ketones occur in adults and children living with diabetes and other medical conditions which may affect these levels. Ketones are acids made by the body when using fats for energy instead of carbohydrates. Study participation includes 2-3 appointments over a period of about 3-6 weeks.

 

Western Minnesota, North Dakota and South Dakota

Sanford – Clinical Trials

(1 of 1) For those with a family history of T1D:

TrialNet screening is offered at no cost to eligible individuals to evaluate their personal risk of developing T1D. This unique screening can identify the early stages of T1D years before any symptoms appear.  It also helps researchers learn more about how T1D develops and plan new studies exploring ways to prevent it. Eligible participants are between the ages of 2.5 and 45 years and have a parent, brother/sister, or child with T1D, between the ages of 2.5 and 20 years and have an aunt/uncle, cousin, grandparent, niece/nephew, or half-brother/sister with T1D and have NOT been diagnosed with T1D.

 

 Virtual Clinical Trials

(1 of 2) For female-identifying T1Ds ages 15-30 experiencing disordered eating:

The Diabetes Body Acceptance Project is conducting a research study comparing two programs designed to improve body acceptance, reduce body image concerns, and reduce disordered eating behaviors. Female-identifying individuals between the ages of 15-30 with T1D who have body image concerns and/or struggle with disordered eating behaviors are invited to participate. Depending on the program you are randomized to you will attend weekly one-hour groups for 6 weeks (virtual for our chapter area) or watch one hour of videos each week.

 

(2 of 2) For T1Ds, loved-ones, and supporters:

The T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for research (for example, by answering questions in annual surveys).  Once enrolled, Registry participants can sign up for other studies on various topics related to type 1 diabetes.

 

Want to stay connected to clinical trials in the future? Check out the T1D Exchange:

https://t1dexchange.org/registry/

 

Meet your Clinical Trials Education Volunteers:

Angie Grant – anggrant@hotmail.com

Debbie Evans – debbieaevans1@gmail.com

 

Updated: 6/18/2025

Clinical Trials Connection