News and Updates

Low blood sugar, called hypoglycemia, is a real fear for people with type 1 diabetes (T1D). Although there are rescue treatments for it, there are no preventive therapies. Zucara Therapeutics, however, may have an answer. It is developing a once-daily therapy that restores glucagon. Adding glucagon raises blood-sugar levels, preventing hypoglycemia and the symptoms that […]

Breakthrough T1D is honored to recognize five leading international researchers whose work has and is transforming type 1 diabetes (T1D) science. We also are proud that our funding has helped drive their work forward toward both curing type 1 diabetes and improving the lives of those living with the disease today. The recipient of the […]

Universal screening for type 1 diabetes (T1D) is a priority for Breakthrough T1D, but the cost versus benefits remain unclear. Now, a large-scale population study in Bavaria, Germany, headed by Breakthrough T1D-funded Anette-Gabriele Ziegler, M.D., Ph.D., has a clue. The Fr1da study of nearly 100,000 children suggests that screening for autoantibodies—antibodies that are directed toward your […]

Low blood sugar, called hypoglycemia, occurs in over 90 percent of people with type 1 diabetes (T1D). It can usually be detected early on, with symptoms such as sweating, fatigue, hunger and/or irritability. In that case, people can eat or drink a fast-acting carbohydrate—like juice or glucose tablets—to bring the blood sugar back to healthy […]

As the leading global funder of type 1 diabetes (T1D) research, Breakthrough T1D invests in the most promising research studies across the world—including more than 70 clinical trials happening right now—to help improve the lives of people with T1D and find cures. That’s a big deal! Let’s take a look at three of them: A […]

Breakthrough T1D is funding work to build a better insulin infusion set; the current infusion sets can be uncomfortable and unreliable, and need to be changed every two to three days. One partner is Pacific Diabetes Technologies, who will test its all-in-one continuous glucose monitoring (CGM) sensor and infusion set in people with type 1 […]

Reza Abdi, M.D., has a reason to care about type 1 diabetes research—he has a father and a brother with the disease. Dr. Abdi, of Brigham and Women’s Hospital in Boston, is an expert in immune therapy research, specifically nanotechnologies—miniscule therapies that can deliver immune treatments to specific regions in the body. His goal: To […]

Sernova, a clinical-stage regenerative medicine company, has shown in its Breakthrough T1D-funded clinical trial that its cell replacement therapy, the Cell Pouch System™, can produce insulin in people with type 1 diabetes (T1D). The technology consists of a dose of purified islet cells transplanted into the Cell Pouch™. The detection of C-peptide, a biomarker of […]

Maribeth Stent was diagnosed with type 1 diabetes (T1D) in the fall of 1997. “It was right around my second birthday,” said Maribeth. She is now a senior coordinator of community engagement at Breakthrough T1D, and she took part in a clinical trial of a hybrid closed loop artificial pancreas system at Yale University in […]

Scientists in Norway are seeking participants for a clinical trial to see if a course of anti-viral treatment may stop beta cell destruction. Pancreatic infection with some viruses, known as enteroviruses, are a likely candidate as one of the environmental causes of type 1 diabetes (T1D). The reason: Evidence of enteroviral infection has been found […]