News and Updates

As the leading global funder of type 1 diabetes (T1D) research, Breakthrough T1D invests in the most promising research studies across the world—including more than 70 clinical trials happening right now—to help improve the lives of people with T1D and find cures. That’s a big deal! Let’s take a look at three of them: A […]

Breakthrough T1D is funding work to build a better insulin infusion set; the current infusion sets can be uncomfortable and unreliable, and need to be changed every two to three days. One partner is Pacific Diabetes Technologies, who will test its all-in-one continuous glucose monitoring (CGM) sensor and infusion set in people with type 1 […]

Reza Abdi, M.D., has a reason to care about type 1 diabetes research—he has a father and a brother with the disease. Dr. Abdi, of Brigham and Women’s Hospital in Boston, is an expert in immune therapy research, specifically nanotechnologies—miniscule therapies that can deliver immune treatments to specific regions in the body. His goal: To […]

Sernova, a clinical-stage regenerative medicine company, has shown in its Breakthrough T1D-funded clinical trial that its cell replacement therapy, the Cell Pouch System™, can produce insulin in people with type 1 diabetes (T1D). The technology consists of a dose of purified islet cells transplanted into the Cell Pouch™. The detection of C-peptide, a biomarker of […]

Maribeth Stent was diagnosed with type 1 diabetes (T1D) in the fall of 1997. “It was right around my second birthday,” said Maribeth. She is now a senior coordinator of community engagement at Breakthrough T1D, and she took part in a clinical trial of a hybrid closed loop artificial pancreas system at Yale University in […]

Scientists in Norway are seeking participants for a clinical trial to see if a course of anti-viral treatment may stop beta cell destruction. Pancreatic infection with some viruses, known as enteroviruses, are a likely candidate as one of the environmental causes of type 1 diabetes (T1D). The reason: Evidence of enteroviral infection has been found […]

BMC Medicine 16: 29 (2018)

Since its discovery nearly 100 years ago, insulin has been the only effective treatment for type 1 diabetes (T1D). Improvements in insulin delivery—from the first human insulin in the 1970s to the introduction of insulin pumps and continuous glucose monitoring (CGM)—have been beneficial, but an overwhelming majority of people with T1D—83% of youth and 79% […]

 Breakthrough T1D funds type 1 diabetes (T1D) clinical trials that are critical to bringing new devices and treatments to people with this disease. Currently, there are more than 70 Breakthrough T1D-funded clinical trials, to both prevent and treat this disease and its complications. We hope that, ultimately, these trials will lead to a cure for […]

Artificial pancreas (AP) systems “close the loop” between continuous glucose monitors and insulin pumps using algorithms to manage insulin. Learn more about Breakthrough T1D's funding of groundbreaking AP technology research.