Recent articles

At the Network for Pancreatic Organ Donors with Diabetes (nPOD) Meeting—its 11th annual and taking place February 19-22—more than 215 people are attending, including some of the most world-renowned diabetes investigators. Many of the latest advances will be discussed—using nPOD samples—to accelerate breakthroughs to cure, prevent, and treat type 1 diabetes (T1D) and its complications. […]

Over the past 50 years, type 1 diabetes (T1D) has increased significantly in many developed countries around the world. There is a genetic component, but genes cannot explain the recent increase in T1D rates, and data suggests that changes in our modern environment have increased the risk for the disease. The human digestive tract hosts […]

  Consider the following: The endo says you’re in DKA with an A1c of 11 and that there’s a chance you’re still in the honeymoon phase. Wait, what? If you’re new to type 1 diabetes (T1D), that probably doesn’t make a whole lot of sense. But these terms are ones that people with T1D have […]

Breakthrough T1D Fiscal Year 2018 Annual Report As you’ll see in the pages of our fiscal year 2018 annual report, together, we are making incredible strides in our fight to cure, prevent and treat type 1 diabetes (T1D) and its complications. In fact, 2018 was one of the most exciting years yet for T1D research. […]

Read the inspiring story of the Teske family and their journey with type 1 diabetes. Learn how their dedication to advocacy and estate planning supports Breakthrough T1D's mission to fund critical research and find a cure.

A protein, called glucokinase (or GK), acts as a key regulator of sugar levels in the body, and its expression is limited to tissues that require sugar-sensing, mainly the liver and pancreatic beta cells. If blood glucose levels are deemed too high, activation of GK in the liver increases glucose utilization which in turn lowers blood glucose.

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