May 21, 2025

Breakthrough T1D, the leading global type 1 diabetes (T1D) research and advocacy organization, submitted an application with the United States Preventive Services Task Force (USPSTF) to secure a recommendation for T1D screening. A recommendation for T1D screening from USPSTF would make screening for T1D part of routine preventive medical services, solidify it as a standard of care, provide guidance for healthcare providers, and ensure coverage of T1D screening by all insurance plans.  

The incidence of T1D is increasing among all populations in the U.S. and around the world. Globally, approximately 9.4 million people live with T1D, and this number is projected to rise to 16.4 million by 2040. While progress has been made in managing T1D, the disease still results in premature death, significant complications, and a substantial daily burden for those affected by it.  

Early detection of T1D through screening, before symptoms appear and insulin is required, can help reduce the risk of life-threatening complications at diagnosis and allow people time to access a therapy that delays onset by an average of two years, participate in crucial T1D clinical trials, and prepare for future medical needs. It can significantly change the course of the disease and improve outcomes for those who are diagnosed with T1D through screening.  Screening can help address the significant unmet needs facing the T1D community that were detailed in a recent Breakthrough T1D journal article

Breakthrough T1D led a community effort of key clinical experts and diabetes patient advocacy organizations to build a strong application to the USPSTF rooted in the nearly three decades of research supporting T1D early detection.   

The USPSTF is an independent body of experts appointed by the U.S. Secretary of Health and Human Services to evaluate and make evidence-based recommendations on how to improve the health of Americans. The USPSTF’s recommendations cover a wide range of preventive services, including screenings, counseling, and medications.  More information about the process, timeline, and application status can be found here at BreakthroughT1D.org