Center of Excellence in
Northern California

About the Center

This Center is a cure accelerator and a high-impact partnership combining the scientific expertise of Stanford University and the University of California, San Francisco (UCSF) within the collaborative structure and support that are hallmarks of Breakthrough T1D. Investigators at the Center will seek to better understand and target the interactions between the immune system and the beta cell, to deliver first-generation, stem cell-based cures for type 1 diabetes (T1D). 

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These world-class researchers will:

• Discover and explain how immune cells interact with islets and beta cells in T1D 
• Generate islets and immune cells from stem cells as the basis for next-generation cell therapies 
• Develop an islet transplant protocol that will induce tolerance and not require immunosuppression