Breakthrough T1D has given Salk scientist Mark Huising a five-year, $750,000 Career Development Award. In pre-clinical models, activation of these receptors has proven to actually prevent diabetes. The goal of Huising’s study, entitled “Urocortin 3 Marks Mature Beta Cells and Prevents Diabetes,” is to understand how this protection against diabetes is accomplished.

“Despite years of research,” he says, “significant gaps remain in our understanding of the way the islet receives and integrates signals from a wide variety of sources. We envision that among these networks of signaling molecules remain plenty that are unknown and can lead to novel strategies to treat or cure Type 1 diabetes.”

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