News and Updates

What’s happening? The U.S. Food and Drug Administration (FDA) approved Tzield (teplizumab-mzwv) for use in children in stage 2 type 1 diabetes (T1D) ages one and older. This is a huge win for the T1D community! Breakthrough T1D applauds the FDA for this approval and Sanofi for their commitment to new therapies for the T1D […]

Karen Shishino Jordan, a long-time volunteer leader in the greater California Bay area, will serve as Breakthrough T1D (formerly JDRF) International Board of Directors (IBOD) Chair, succeeding current Chair Lisa Fishbone Wallack. Carlton McMillan, also a dedicated volunteer leader in the greater California Bay area, will serve as Vice Chair, succeeding current Vice Chair Matt Varey.     Karen’s and Carlton’s terms as Chair and Vice Chair, respectively, begin Wednesday, July 1, 2026.    Breakthrough […]

Breakthrough T1D is focused on developing drugs, or disease-modifying therapies (DMTs), that change the course of T1D for everyone affected by it—and those yet to be. That means slowing or halting the progression of the disease, preventing it from ever occurring, and reversing it entirely through immune therapies and beta cell therapies.  Note: To enlarge the image below, left click […]

Breakthrough T1D is back from Barcelona! The final two days of ATTD were jam-packed with more incredible updates across all areas of our mission. Breakthrough T1D staff chaired and participated in many sessions—including Breakthrough T1D Senior Vice President of Research, Esther Latres, Ph.D.; Vice President of Medical Affairs Anastasia Albanese O’Neill, Ph.D., APRN, CDCES; Senior […]

Greetings from Barcelona, Spain! From March 11–14, 2026, the world’s leading type 1 diabetes (T1D) researchers, healthcare professionals, and industry partners gathered to share groundbreaking advances in T1D science—and Breakthrough T1D–supported work (and staff) were front and center. Below is everything you need to know from the first two days of this remarkable conference, including […]

Our Statement on Deceased Donor Islet Cell Availability & The ISLET Act Curing type 1 diabetes (T1D) is Breakthrough T1D’s number one priority. As the leading global T1D research and advocacy organization, we are currently funding over $450 million in cures research in 23 countries. Everything we do is focused on making cures happen for the T1D […]

Tzield is the first approved disease-modifying therapy for type 1 diabetes, but Breakthrough T1D will make sure it’s not the last.

Learn the basics about autoimmune disease, including prevalence in the U.S., possible causes, and why they are often called "invisible."

One of our most promising avenues toward cures for type 1 diabetes (T1D) is cell therapies. Cell therapies replace destroyed beta cells with functional, insulin-producing cells to restore insulin therapy independence. Right now, there are nearly a dozen cell therapies in clinical testing—and OPF-310 is one of them. OPF-310 cells are derived from porcine (pig) […]

Breakthrough T1D created a guide for sensor issues, from what to do if symptoms and CGM reading do not match to how to get a replacement.