Meet the Scientist: Developing Devices That Resist Autoimmune Attacks
What might be the next best thing to having a healthy pancreas that is steadily producing insulin? It could be a device inside a person’s body that would protect the implanted beta cells from attack, while allowing the cells to produce insulin for you. Dan Anderson, Ph.D., has been working for years to create devices […]
T1D Research Continues During Coronavirus
Quite quickly, the coronavirus pandemic has disrupted daily life, jolted perspectives and could very well change how we work and interact with each other for a long time to come. But what has the impact been inside research labs, where Breakthrough T1D-funded scientists have been driving hard and fast to deliver cures for type 1 […]
Coating on Capsules Next Step in Creating Insulin-Producing Factories
One potential cure for type 1 diabetes (T1D) is to replace beta cells destroyed by a person’s own immune system with healthy transplanted beta cells inside a device, which would then be placed inside the person’s body. Encapsulated cells would release insulin in response to changes in glucose levels. That is exactly the scenario that […]
Zucara Faces “Valley of Death,” and Comes Out Triumphant
Low blood sugar, called hypoglycemia, is a real fear for people with type 1 diabetes (T1D). Although there are rescue treatments for it, there are no preventive therapies. Zucara Therapeutics, however, may have an answer. It is developing a once-daily therapy that restores glucagon. Adding glucagon raises blood-sugar levels, preventing hypoglycemia and the symptoms that […]
England, Today and Onward, to Provide Pregnant Women with CGM Technology
It’s a milestone for pregnant women with type 1 diabetes (T1D) and Breakthrough T1D. Today and onward, the National Health Service (NHS) England will provide continuous glucose monitoring (CGM) to pregnant women with T1D. This is something that Breakthrough T1D can be proud of—evidence for it came from the Breakthrough T1D-funded CONCEPTT study, which proved […]
New Research Suggests that T1D Has Two Distinct Types
Breakthrough T1D-funded researchers found that type 1 diabetes is comprised of two different subtypes, called endotypes, which are dependent upon the age at diagnosis.
Strengthening Type 1 Diabetes Science by Building Careers
Sometimes, the funding that Breakthrough T1D can provide for researchers is exactly the invitation they need to get into the field of type 1 diabetes (T1D) research. Other times, sustained grants are the critical boost that someone with more experience needs in order to branch out and establish his or her own lab. Creating and […]
TTP399: A Potential First-in-Class Adjunct Therapy in Type 1 Diabetes
Nearly 80 percent of people with type 1 diabetes (T1D) fail to meet HbA1c goals defined by the American Diabetes Association. Despite more widely adopted diabetes technology and an increase in use, there is no improvement in clinical outcomes. This tells us that the current use of insulin alone is not enough, but vTv Therapeutics […]
Saving Vision, Changing Lives
Several decades ago, type 1 diabetes (T1D) patients brought their seeing-eye dogs into the offices where Jennifer Sun, M.D., MPH., now works. The complications of T1D had severely compromised or cost the patients their eyesight. Today, work led by Dr. Sun is changing all that. We share Dr. Sun’s work as part of our Meet […]
A Scientist Sees Kidney Disease Through New Eyes
Monika Niewczas is keenly focused on kidneys. Specifically, making sure that they don’t stop working when someone develops type 1 diabetes (T1D). Niewczas, an M.D., Ph.D. and M.P.H., works as an assistant investigator at Joslin Diabetes Center and an assistant professor of medicine at Harvard Medical School. For the past 15 years, she has worked […]
