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Breakthrough T1D Fiscal Year 2018 Annual Report As you’ll see in the pages of our fiscal year 2018 annual report, together, we are making incredible strides in our fight to cure, prevent and treat type 1 diabetes (T1D) and its complications. In fact, 2018 was one of the most exciting years yet for T1D research. […]

A protein, called glucokinase (or GK), acts as a key regulator of sugar levels in the body, and its expression is limited to tissues that require sugar-sensing, mainly the liver and pancreatic beta cells. If blood glucose levels are deemed too high, activation of GK in the liver increases glucose utilization which in turn lowers blood glucose.

You’ll hear it again and again: For some people with type 1 diabetes (T1D), SGLT inhibitor therapy* means taking less insulin, having increased time in range, reducing the minute-to-minute glucose variability, contributing to weight loss and lowering your A1c. But you’ll also hear about the risks. From dehydration and constant urination to urinary tract infections […]

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