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Leading the way to life-changing therapies and cures
Curing T1D. Improving Lives.
As the leading global type 1 diabetes (T1D) research and advocacy organization, we help make everyday life with T1D better while driving toward cures.
Since our founding in 1970, Breakthrough T1D has funded more than $2.5 billion in research, and our advocacy work has resulted in nearly $3.5 billion in additional research funding from the U.S. government. We propel research—from basic science to clinical trials—in key therapy areas to improve lives and drive toward cures for type 1 diabetes.
Research to Cure Type 1 Diabetes
We don’t have cures that restore insulin independence for people with T1D yet, but we know to make them a reality we need to restore the body’s ability to make insulin and turn off the autoimmune attack responsible for destroying the beta cells.
To achieve this, Breakthrough T1D’s cures portfolio is focused on three areas:
Develop a global universal T1D early detection strategy to identify high-risk individuals, reduce diabetic ketoacidosis (DKA) at diagnosis, and speed up the development of disease-modifying therapies.
Powering the research and development of new therapies that can slow, halt, or reverse the course of T1D.
Investing in research and clinical trials to develop life-changing therapies that insert healthy insulin-producing cells into people with T1D with minimal or no immunosuppression.
Breakthrough T1D is focused on the entire T1D continuum, from those who don’t have T1D to those who have lived with it for decades.”
Research to Improve Everyday Life with T1D
People living with type 1 diabetes must have tools, therapies, and interventions to keep them healthy so that as cures come to fruition, they are healthy enough to take advantage of them.
To achieve this, Breakthrough T1D’s improving lives portfolio is focused on two areas:
Making T1D easier to manage with improved technology, insulins, and other drugs.
Discovering therapies that intervene in heart, eye, and kidney disease and reducing the mental burden of T1D through research and clinical trials.
My loved ones with T1D have a quality of life and life expectancy unimaginable a generation ago. Breakthrough T1D has the research strategy and tools that will allow my loved ones to walk away from this disease, and I believe the next generation of my family will never know the burden of T1D.”
Learn More About Our Research
Breakthrough T1D doesn’t have laboratories; we work with the top minds all over the world to solve T1D’s biggest challenges. Together, we’re working to make type 1 diabetes a thing of the past.
We are powering research to cure, prevent, and better treat type 1 diabetes and its complications. This is our strategy to do it.
Search our abstract database for past research funding information, or see where Breakthrough T1D’s nearly 500 active grants are driving progress today.
Breakthrough T1D offers a wide variety of grants and fellowships to researchers. All qualified scientists are encouraged to apply.
Breakthrough T1D recognizes individuals who have significantly advanced our mission. Learn about our Research Awards and the trailblazers who have received them.
Clinical Trials: Critical to Advancing T1D Research
Clinical trials advance care so people living with T1D can live fuller, healthier lives. Learn more about how you can further research and drive us toward a future without T1D.
Type 1 Diabetes Research News
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