Investigations by Leading Immune-Mediated Disease Research Organizations
Breakthrough T1D has partnered with the Lupus Research Alliance and the National Multiple Sclerosis Society to advance the understanding of autoimmunity.
Breakthrough T1D Launches Third Center of Excellence in New England
The Breakthrough T1D New England Center of Excellence will focus on protecting the stem cell-derived beta cells from rejection by the immune system after transplantation.
Can a Psoriasis Drug Halt or Reverse Type 1 Diabetes?
Type 1 diabetes is one of the only major autoimmune diseases that doesn't have a disease-modifying therapy. A Breakthrough T1D clinical trial is aiming to change that.
Vertex Has a New Horizon: Curing Type 1 Diabetes
Vertex Pharmaceuticals will launch a clinical trial of VX-880, a stem cell-derived beta cell therapy in type 1 diabetes (T1D).
Why Does One Scientist Seek to Find Cures for T1D? Answer: His Children
Douglas Melton, Ph.D., can now produce unlimited quantities of beta cells. He now wants to evade the immune attack. See our video to find out more.
It’s Official: Teplizumab is Under Review by the FDA
The FDA regulatory review is now under way for teplizumab, to prevent or delay T1D in at-risk individuals. The target action date is July 2, 2021.
What We Can Be Proud Of in 2020
It’s been a tough year, to say the least. But there’s news that we can be proud of in type 1 diabetes research and advocacy. Really proud of.
Breakthrough T1D Video: “Wouldn’t Have Happened Without Breakthrough T1D”
Dr. Robert Langer co-founded Moderna, who gained emergency use approval for its COVID vaccine. Watch the video to find out how Breakthrough T1D is helping to advance his research.
Discovery to Translation: Clinical Trial of a JAK Inhibitor in T1D
A Breakthrough T1D-funded clinical trial will test if a JAK inhibitor will preserve beta cell function in children and young adults with recently diagnosed T1D.
Breakthrough T1D Video: “We’ve Been Too Focused on [Insulin]”
“We’ve been too focused on [insulin],” Jeremy Pettus, M.D., an endocrinologist at UC San Diego, says. Watch the video to find out why.
