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Bridget Wagner, Ph.D., is a chemical biologist who wants to find a compound that can repopulate the beta cells that have been lost in type 1 diabetes (T1D).

Leading researchers from around the world will gather for the annual meeting of the European Association for the Study of Diabetes (EASD). At this year’s meeting, which will take place virtually from September 22-25, more than 40 studies will be presented by Breakthrough T1D researchers, funded now or in the past, working to find cures […]

In the words of Colin Dayan, M.D., Ph.D., professor of clinical diabetes and metabolism at Cardiff University: “Type 1 diabetes is almost the only major autoimmune disease now that does not have a licensed immunotherapy.” And he’s going to change that.

Accurate control of blood sugar for people with type 1 diabetes (T1D) was not easy in the 1970s. At the time, the degree of diabetes control relied on patient history, urinary sugar and blood-sugar measurement at the time of the doctor’s visit. There was nothing that could tell you what your blood-sugar levels were for […]

The Food and Drug Administration (FDA) approved the Medtronic MiniMed 770G artificial pancreas system for use by children aged 2 to 6 with type 1 diabetes (T1D). It is the first marketed device that can automatically adjust insulin delivery based on continuous glucose monitoring (CGM) values for children aged 2-6 years.

A clinical trial at four pediatric diabetes centers in the United States has found that a new artificial pancreas system—which automatically monitors and regulates blood-sugar levels—is safe and effective in children as young as age six with type 1 diabetes (T1D): Tandem’s t:slim X2™ insulin pump with Control-IQ™ technology. The algorithm in the Control-IQ technology […]

While genetics play a major role in the development of type 1 diabetes (T1D), mounting evidence supports the strong influence of the intestinal environment—called the microbiome—in this disease. Nevertheless, few “microbiome-based” strategies have been tested in clinical trials. Recently, Graciela Lorca, Ph.D., professor of microbiology at the University of Florida, found that one bacterial strain—a […]

You’re going to hear about a part of your body that, really, goes unnoticed in type 1 diabetes (T1D): blood vessels. But blood vessels are everywhere. From your eye to your lungs to even your pancreas. And they’re really, really important. Do you know that these vessels transport blood cells, nutrients and oxygen to all […]

Type 1 diabetes (T1D) can be hard to predict in high risk children. Testing for the presence of T1D autoantibodies—antibodies against one’s own proteins—helps reduce the incidence of diabetic ketoacidosis (DKA)—a common occurrence in children upon diagnosis, that can lead to death if not treated—but this testing is not widely available. While having 2 or […]