The Power of the Patient Voice: Breakthrough T1D Video
In the words of Colin Dayan, M.D., Ph.D., professor of clinical diabetes and metabolism at Cardiff University: “Type 1 diabetes is almost the only major autoimmune disease now that does not have a licensed immunotherapy.” And he’s going to change that.
Breakthrough T1D Report: How HbA1c Came to Be
Accurate control of blood sugar for people with type 1 diabetes (T1D) was not easy in the 1970s. At the time, the degree of diabetes control relied on patient history, urinary sugar and blood-sugar measurement at the time of the doctor’s visit. There was nothing that could tell you what your blood-sugar levels were for […]
FDA Approves an Artificial Pancreas System for Children Aged 2-6 Years
The Food and Drug Administration (FDA) approved the Medtronic MiniMed 770G artificial pancreas system for use by children aged 2 to 6 with type 1 diabetes (T1D). It is the first marketed device that can automatically adjust insulin delivery based on continuous glucose monitoring (CGM) values for children aged 2-6 years.
Tandem Control-IQ Improves T1D Management in Children Ages 6 and Up
A clinical trial at four pediatric diabetes centers in the United States has found that a new artificial pancreas system—which automatically monitors and regulates blood-sugar levels—is safe and effective in children as young as age six with type 1 diabetes (T1D): Tandem’s t:slim X2™ insulin pump with Control-IQ™ technology. The algorithm in the Control-IQ technology […]
Microbiome Reset: Clinical Trial in Newly Diagnosed Youth
While genetics play a major role in the development of type 1 diabetes (T1D), mounting evidence supports the strong influence of the intestinal environment—called the microbiome—in this disease. Nevertheless, few “microbiome-based” strategies have been tested in clinical trials. Recently, Graciela Lorca, Ph.D., professor of microbiology at the University of Florida, found that one bacterial strain—a […]
Solving Big Challenges in Beta Cell Transplantation
You’re going to hear about a part of your body that, really, goes unnoticed in type 1 diabetes (T1D): blood vessels. But blood vessels are everywhere. From your eye to your lungs to even your pancreas. And they’re really, really important. Do you know that these vessels transport blood cells, nutrients and oxygen to all […]
Breakthrough T1D Researchers Develop a Combined Risk Score to Predict Which Children Develop T1D
Type 1 diabetes (T1D) can be hard to predict in high risk children. Testing for the presence of T1D autoantibodies—antibodies against one’s own proteins—helps reduce the incidence of diabetic ketoacidosis (DKA)—a common occurrence in children upon diagnosis, that can lead to death if not treated—but this testing is not widely available. While having 2 or […]
Cell Therapy Approaches Moving Along the Pipeline
Beta cell replacement therapies for type 1 diabetes (T1D) have made significant advances in just the past 10 years. We now have insulin-producing beta cells, derived from stem cells, which makes a donor (needed to provide the beta cells) obsolete. We have seen that stem cell-derived precursors can—once implanted in humans—mature into beta cells and […]
Accelerating Our Mission and Becoming More Volunteer Powered
Our bold vision for the future outlines strategies to drive greater impact to unlock cures and drive research that improves the lives of people with type one diabetes (T1D).
Myth vs. Fact: COVID-19 Can Trigger Diabetes
It’s been around the news: COVID-19 might trigger diabetes, at least in some people. That’s what several Breakthrough T1D-funded scientists posit. But let’s look at the evidence.
