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Vertex

It’s an exciting time for type 1 diabetes (T1D) research. Nearly every day, we’re seeing incredible progress across each area of Breakthrough T1D’s research portfolio to cure, prevent, and treat T1D and its complications. One area in particular is making headlines: Cell therapies.  In T1D, the immune system destroys the beta cells in the pancreas, which produce insulin. Cell therapies aim to replace […]

A large group of people sit on a couch while more people stand behind them. All are posing for the camera.

Remember how fun it was to be on the couch with your friends, fire up your Nintendo console, and play video games late into the night? Heroes of Time captures that magic but adds in 33 talented creators, a massive audience, and creative fundraising. It’s all in support of Breakthrough T1D Play and our work […]

Two people on bicycles giving thumbs up at a Breakthrough T1D Ride event

Breakthrough T1D Ride is a charitable cycling event that has raised over $77 million for type 1 diabetes (T1D) research, which has directly led to innovations like continuous glucose monitors (CGMs) and disease-modifying therapies that can slow the progression of T1D. Ride offers cyclists of every age and skill level the chance to fuel breakthroughs […]

A massive crowd of people moves through an inflatable arch reading "Breakthrough T1D Walk."

Breakthrough T1D Walk is a nationwide movement dedicated to raising type 1 diabetes (T1D) awareness and funding research. As the largest T1D walk, this event empowers individuals and teams to take action. But we couldn’t do it alone—our local volunteers make each event possible! That includes Casey Adams, Corporate Committee Co-Chair for the Los Angeles […]

Two doctors review a patient chart

Breakthrough T1D is focused on developing drugs, or disease-modifying therapies (DMTs), that change the course of T1D for everyone affected by it—and those yet to be. That means slowing or halting the progression of the disease, preventing it from ever occurring, and reversing it entirely through immune therapies and beta cell therapies.  Note: To enlarge the image below, left click […]

Young man injects insulin using an insulin pen

Type 1 diabetes (T1D) occurs when the body’s immune system attacks the insulin-producing beta cells in the pancreas. But this doesn’t happen overnight—instead, it’s a gradual process of beta cell loss over time. As the immune system attacks and destroys more beta cells, insulin production decreases, leading to abnormal blood-sugar levels. Eventually, enough beta cells are […]

Type 1 Diabetes Advocacy

From March 15–18, more than 200 passionate, motivated Breakthrough T1D Advocates from all 50 states convened in Washington, D.C., for Breakthrough T1D 2026 Government Day. Government Day remains one of Breakthrough T1D’s most impactful ways to effect change. By bringing the lived type 1 diabetes (T1D) experience directly to policymakers, we are accelerating progress toward […]

Two adults support one another by holding hands

Autoimmune diseases occur when a person’s immune system wrongly attacks the body’s healthy cells, tissues, and organs. This response can result in a range of conditions, depending on which parts of the body are affected. Autoimmune diseases are often called “invisible” because their symptoms are not always evident to the people around you. As a […]

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